Mathematical Virology

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Mathematical Virology

 06 - 10 Aug 2007

ICMS

  • Peter Stockley, University of Leeds
  • Reidun Twarock, University of York

About:

This interdisciplinary workshop brought together high-profile researchers as well as young scientists and research students to discuss challenges at the forefront of virology. This workshop focused on important aspects of virus research such as the structure and physical properties of viruses. As a result of this workshop, a number of new collaborations were formed within and across discipline boundaries, and new experimental and theoretical approaches were inspired. The main focus of the workshop was on structure and assembly of viral capsids and the packaging of the viral genome.

Spealkers

Mavis Agbandje-McKenna, University of Florida - Elucidating the Structural Mechanisms of Spherical Viral Capsid Assembly for ssDNA Viruses  

Javier Arsuaga, San Francisco State University - DNA Knots from Bacteriophage P4 Suggest a Chromosomal Organisation with High Writhe Values  

Dennis Bamford, University of Helsinki - What Are the Ways to Assemble a Virion - Lessons from Nature  

Charles Brooks, Scripps Research Institute - Exploring Viral Capsid Assembly, Mechanics and Dynamics

Robijn Bruinsma, University of California - Physics and the HIV Virus

Paolo Carloni, SISSA - Hybrid Coarse-Grain/Molecular Mechanics Approach for the Investigation of Viral and Bacterial Proteins  

Karim ElSawy, University of York - Towards an Understanding of Assembly Polymorphism in Papovaviridae Viruses from an Energy Landscape

Alex Evilevitch, Lund University - Internal DNA Pressure Effect on Phage Capsid Stability and Infectivity  

Robert Garcea, University of Colorado School of Medicine - Confounding Biologic Variables in Modeling Virus Assembly  

William Gelbart, University of California - Sizes of Viral Genomes and Viral Capsids  

Roger Hendrix, University of Pittsburgh - Viral Capsid Assembly: the Evolutionary Dimension  

Aloysio Janner, Radboud University Nijmegen - Exploring the Interplay Between Molecular Crystallography and Geometrical Virology  

Jack Johnson, Scripps Research Institute - Biophysical Analysis of Virus Particles and their Maturation: Insights Into Elegantly Programmed Nanomachines  

Thomas Keef, University of York - A Hamiltonian Paths Approach to Viral Capsid Assembly of RNA Viruses  

Willem Kegel, Utrecht University - Charge Regulation as a Stabilization Mechanism for Shell-Like Assemblies

Richard Kerner, University of Paris-VI - Evolutionary Trends in Icosahedral Virus Capsids: a Combinatorial Approach 

Alexander McPherson, University of California - Conformation of RNA in Small Icosahedral Viruses  

Ranjan Mannige, Scripps Research Institute - Constraints and Freedoms in Virus Capsids: a Theoretical Perspective  

Davide Marenduzzo, University of Edinburgh - The Dynamics of Polymer Packaging and Ejection in Viral Capsids  

Cristian Micheletti, SISSA - Common Large-Scale Movements in HIV-1 Protease and Other Proteolytic Enzymes: a Coarse-Grained Approach  

David Nelson, Harvard University - Deformations of Viral Shells by Point Forces and Osmotic Pressure  

Hung D Nguyen, Scripps Research Institute - Towards Understanding of Structural Polymorphism and Precise Control of Viral Capsid Self-Assembly  

Ariella Oppenheim, Hebrew University of Jerusalem - SV40 Assembly in Vivo and in Vitro  

Peter Prevelige, University of Alabama - Incorporation of the Portal Protein Complex into Bacteriophage Phi-29  

Dennis Rapaport, Bar-Ilan University - Interactively Exploring Supramolecular Assembly: a Molecular Dynamics Approach to Virus Construction  

David Reguera, Universitat de Barcelona - Hysteresis and Kinetics of Viral Self-Assembly  

Ottar Rolfsson, University of Leeds - Probing MS2 Capsid Assembly with ESI-MS

Paul van der Schoot, Eindhoven University of Technology - Modified Zipper Model for the Self Assembly of Tobacco Mosaic Virus  

Meera Sitharam, University of Florida - Static Modeling of Virus Assembly Pathway Probabilities  

Russell Schwartz, Carnegie Mellon University - Exploring Capsid Assembly Pathways through Continuous-Time Discrete Event Simulation  

De Witt Sumners, Florida State University - DNA Knots Reveal Chiral Packing of DNA in Phage Capsids  

Alasdair Steven, National Institutes of Health - Stochastically Variable Virus Structure  

Nicola Stonehouse, University of Leeds - Phi29 – Investigating a DNA Packaging Motor  

Anne Taormina, Durham University - Vibrational Modes of Viral Capsids and Viral Tiling Theory  

Katerina Toropova, University of Leeds - The 3D Structure of Genomic RNA in Bacteriophage MS2; Implications for Assembly

Roman Tuma, University of Helsinki - Stochastic Aspects of RNA Packaging Motor: from Single Molecule Experiments to High Resolution Structure  

Reidun Twarock, University of York - A Symmetry Approach to the Three-Dimensional Structure of Simple Viruses David Wales, University of Cambridge - Energy Landscapes and Self-Assembly of Icosahedral Shells  

Adam Zlotnick, University of Oklahoma Health Sciences Center - How Much Do You Need to Know to Describe Virus Assembly?