Stochastic, Statistical and Computational Approaches to Immunology

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Stochastic, Statistical and Computational Approaches to Immunology

 22 - 26 Jul 2013

ICMS, 15 South College Street Edinburgh

Scientific Organisers:

  • Arup Chakraborty, Massachusetts Institute of Technology
  • Daniel Coombs, University of British Columbia
  • Ken Duffy, Maynooth University
  • Carmen Molina-Paris, University of Leeds

Session Chair:

  • Rajat Varma, National Institutes of Health/NIAID
  • Arup Chakraborty, Massachusetts Institute of Technology
  • Dan Coombs, University of British Columbia
  • Miles Davenport, University of New South Wales
  • Roland Regoes, ETH Zurich
  • Ben Seddon, MRC National Institute for Medical Research
  • Leila Perié, Utrecht University

About:

The primary objective was to continue the current effort in mathematical immunology that was initiated by a series of international meetings. The second objective was to enhance and train the British mathematical immunology community. The workshop brought state-of-the-art knowledge to the UK community, improved communication between the two main groups involved (immunologists and mathematicians) and lastly, disseminated new results and encouraged novel approaches to existing problems.

Speakers:

  • Arup Chakraborty, Massachusetts Institute of Technology - How to Hit HIV Where it Hurts

  • Miles Davenport, University of New South Wales - Mechanisms of Age-Associated Immunity to P. Falciparum Malaria

  • Daniel Coombs, University of British Columbia - Branching Process Models for HIV and SIV Infection

  • Roland Regoes, ETH Zurich - Lymph Node Colonisation Dynamics After Oral Salmonella Typhimurium Infection in Mice  

  • Simeone Marino, University of Michigan - Hybrid Computational Models of Granuloma Formation During Tuberculosis Infection

  • Rajat Varma, National Institutes of Health/NIAID - TCR Microclusters as Platforms for Ligand Discrimination

  • Brian Evavold, Emory University - Two-Dimensional Affinity Range of Antigen Specific Regulatory T Cells

  • Omer Dushek, University of Oxford - Systems Model of T Cell Receptor Proximal Signalling Reveals Emergent Ultrasensitivity

  • Cheng Zhu, Georgia Institute of Technology - Antigen-Specific TCRpMHC Catch Bond Enables Force to Trigger T Cell Signalling

  • Deborah Dunn-Walters, King's College London - Human B Cell Repertoires: Age Challenges

  • Deborah Cromer, University of New South Wales - Estimating Cytomegalovirus Growth Rates by Using Only a Single Point

  • Nick Savill, University of Edinburgh - How Maternally Transferred Immunity Alters Rodent Malaria Infection Dynamics and Protects Against Death

  • Floriane Lignet, INRIA - Mathematical Modelling of in Vivo CD8 T Cell Proliferation

  • Thomas Höfer, DKFZ - Inferring the Program of T Cell Diversification From in Vivo Fate Mapping

  • Leila Perié, Utrecht University - Single Cell Tracing of Hematopoiesis Using Cellular Barcoding

  • Ken Duffy, National University of Ireland - Competition, Censorship and Cell Fates

  • Joost Beltman, Netherlands Cancer Institute - The Role of Subtle Directed Migration During Immune Responses
  • Grant Lythe, University of Leeds - Stochastic Dynamics and the Adaptive Immune System
  • Giorgio Guzzetta, Trento Rise - The Role of Ageing and Immune Memory in the Outcome of Mycobacterium Tuberculosis Infection
  • Tom Weber, National University of Ireland - Flux Analysis Indicates G2 Dependent Immigration Into the Dark Zone of Germinal Centres
  • Edwin Hawkins, Imperial College London - Construction and Application of the Cyton Model of Lymphocyte Responses: Quantitative Analysis of Fate Regulation in Lymphocytes
  • Neil Dalchau, Microsoft Research - Conformational Change of MHC Class I Molecules is Required for Efficient Antigen Presentation
  • Martín López García, Complutense University of Madrid - Extreme Values in Competition Processes 
  • Ben Seddon, MRC National Institute for Medical Research - Selected but Neglected: Alternative Fates for Thymocytes Undergoing Positive Selection in the Thymus

  • Carmen Molina-París, University of Leeds - Modelling Immune Processes at the Molecular, Cellular and Population Levels 
  • Andrew Yates, Albert Einstein College of Medicine - Life Choices for T Cells: Decision-Making and Optimal Strategies, from Development to Maturity
  • Juliane Liepe, Imperial College London - Moving Towards Understanding of Leukocyte Migration
  • Hannah Mayer, University of Bonn - A Stochastic Model of T Cell Activation
  • Elena Abad, Universitat Pompeu Fabra - Dynamics of CD4 T Cells Activation in EAE Mice Model